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Sprouty4 regulates endothelial cell migration via modulating Integrin β3 stability through c-Src

Angiogenesis is mediated by signaling through receptor tyrosine kinases (RTKs), Src family kinases and adhesion receptors such as integrins, yet the mechanism how these signaling pathways regulate one another remains incompletely understood. The RTK modulator, Sprouty4 (Spry4) inhibits endothelial c...

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Detalhes bibliográficos
Main Authors: Gong, Yan, Yang, Xuehui, He, Qing, Gower, Lindsey, Prudovsky, Igor, Vary, Calvin P.H., Brooks, Peter C., Friesel, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790316/
https://ncbi.nlm.nih.gov/pubmed/23955631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-013-9361-x
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