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Upregulation of genes related to bone formation by γ-amino butyric acid and γ-oryzanol in germinated brown rice is via the activation of GABA(B)-receptors and reduction of serum IL-6 in rats

BACKGROUND: Osteoporosis and other bone degenerative diseases are among the most challenging non-communicable diseases to treat. Previous works relate bone loss due to osteoporosis with oxidative stress generated by free radicals and inflammatory cytokines. Alternative therapy to hormone replacement...

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Autors principals: Muhammad, Sani Ismaila, Maznah, Ismail, Mahmud, Rozi, Zuki, Abu Bakar Zakaria, Imam, Mustapha Umar
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789840/
https://ncbi.nlm.nih.gov/pubmed/24098073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CIA.S45943
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