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Mono and Dual Cofactor Dependence of Human Cystathionine β-Synthase Enzyme Variants In Vivo and In Vitro

Any two individuals differ from each other by an average of 3 million single-nucleotide polymorphisms. Some polymorphisms have a functional impact on cofactor-using enzymes and therefore represent points of possible therapeutic intervention through elevated-cofactor remediation. Because most known d...

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Autori principali: Dimster-Denk, Dago, Tripp, Katherine W., Marini, Nicholas J., Marqusee, Susan, Rine, Jasper
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789787/
https://ncbi.nlm.nih.gov/pubmed/23934999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.113.006916
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