Genome-Wide Association Study of Gene by Smoking Interactions in Coronary Artery Calcification

Many GWAS have identified novel loci associated with common diseases, but have focused only on main effects of individual genetic variants rather than interactions with environmental factors (GxE). Identification of GxE interactions is particularly important for coronary heart disease (CHD), a major...

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Autores principales: Polfus, Linda M., Smith, Jennifer A., Shimmin, Lawrence C., Bielak, Lawrence F., Morrison, Alanna C., Kardia, Sharon L. R., Peyser, Patricia A., Hixson, James E.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789744/
https://ncbi.nlm.nih.gov/pubmed/24098343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074642
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