Daily Acyclovir to Decrease Herpes Simplex Virus Type 2 (HSV-2) Transmission from HSV-2/HIV-1 Coinfected Persons: A Randomized Controlled Trial

Background. Daily suppressive therapy with valacyclovir reduces risk of sexual transmission of herpes simplex virus type 2 (HSV-2) in HSV-2–serodiscordant heterosexual couples by 48%. Whether suppressive therapy reduces HSV-2 transmission from persons coinfected with HSV-2 and human immunodeficiency...

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Main Authors: Mujugira, Andrew, Magaret, Amalia S., Celum, Connie, Baeten, Jared M., Lingappa, Jairam R., Morrow, Rhoda Ashley, Fife, Kenneth H., Delany-Moretlwe, Sinead, de Bruyn, Guy, Bukusi, Elizabeth A., Karita, Etienne, Kapiga, Saidi, Corey, Lawrence, Wald, Anna, Lingappa, Jairam, Campbell, Mary, Coombs, Robert W., Hughes, James P., Magaret, Amalia, McElrath, M. Juliana, Morrow, Rhoda, Mullins, James I., Coetzee, David, Fife, Kenneth, Were, Edwin, Essex, Max, Makhema, Joseph, Katabira, Elly, Ronald, Allan, Kayitenkore, Kayitesi, Bukusi, Elizabeth, Cohen, Craig, Kanweka, William, Allen, Susan, Vwalika, Bellington, Manongi, Rachel, Farquhar, Carey, John-Stewart, Grace, Kiarie, James, Inambao, Mubiana, Farm, Orange, Rees, Helen, Gray, Glenda, McIntyre, James, Rwamba Mugo, Nelly
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789565/
https://ncbi.nlm.nih.gov/pubmed/23901094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit333
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