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Systemic and Nonrenal Adverse Effects Occurring in Renal Transplant Patients Treated with mTOR Inhibitors

The mammalian target of rapamycin inhibitors (mTOR-I), sirolimus and everolimus, are immunosuppressive drugs largely used in renal transplantation. The main mechanism of action of these drugs is the inhibition of the mammalian target of rapamycin (mTOR), a regulatory protein kinase involved in lymph...

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Detalhes bibliográficos
Main Authors: Zaza, Gianluigi, Tomei, Paola, Ria, Paolo, Granata, Simona, Boschiero, Luigino, Lupo, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789319/
https://ncbi.nlm.nih.gov/pubmed/24151517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/403280
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