U6 is unsuitable for normalization of serum miRNA levels in patients with sepsis or liver fibrosis

MicroRNA (miRNA) levels in serum have recently emerged as potential novel biomarkers for various diseases. miRNAs are routinely measured by standard quantitative real-time PCR (qPCR); however, the high sensitivity of qPCR demands appropriate normalization to correct for nonbiological variation. Pres...

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Detalhes bibliográficos
Main Authors: Benz, Fabian, Roderburg, Christoph, Vargas Cardenas, David, Vucur, Mihael, Gautheron, Jérémie, Koch, Alexander, Zimmermann, Henning, Janssen, Jörn, Nieuwenhuijsen, Lukas, Luedde, Mark, Frey, Norbert, Tacke, Frank, Trautwein, Christian, Luedde, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789266/
https://ncbi.nlm.nih.gov/pubmed/24052167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2013.81
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