Drug-primed reinstatement of cocaine seeking in mice: increased excitability of medium-sized spiny neurons in the nucleus accumbens

To examine the mechanisms of drug relapse, we first established a model for cocaine IVSA (intravenous self-administration) in mice, and subsequently examined electrophysiological alterations of MSNs (medium-sized spiny neurons) in the NAc (nucleus accumbens) before and after acute application of coc...

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Detalhes bibliográficos
Main Authors: Ma, Yao-Ying, Henley, Sandy M., Toll, Jeff, Jentsch, James D., Evans, Christopher J., Levine, Michael S., Cepeda, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Neurochemistry 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789142/
https://ncbi.nlm.nih.gov/pubmed/24000958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/AN20130015
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