A Phase II, Randomized, Double-Blind, Placebo Controlled, Dose-Response Trial of the Melatonin Effect on the Pain Threshold of Healthy Subjects

BACKGROUND: Previous studies have suggested that melatonin may produce antinociception through peripheral and central mechanisms. Based on the preliminary encouraging results of studies of the effects of melatonin on pain modulation, the important question has been raised of whether there is a dose...

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Main Authors: Stefani, Luciana Cadore, Muller, Suzana, Torres, Iraci L. S., Razzolini, Bruna, Rozisky, Joanna R., Fregni, Felipe, Markus, Regina, Caumo, Wolnei
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3788771/
https://ncbi.nlm.nih.gov/pubmed/25947930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074107
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