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Autocrine motility factor stimulates the invasiveness of malignant cells as well as up-regulation of matrix metalloproteinase-3 expression via a MAPK pathway

The autocrine motility factor (AMF) is a multifunctional protein that is involved in tumor progression including enhanced invasiveness via induction of matrix metalloproteinase-3 (MMP3). The increase in MMP3 was found in an AMF-high production tumor cell line, and c-Jun, c-Fos and mitogen-activated...

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Detalhes bibliográficos
Main Authors: Haga, Arayo, Funasaka, Tatsuyoshi, Deyashiki, Yoshihiro, Raz, Avraham
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3788612/
https://ncbi.nlm.nih.gov/pubmed/18485900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2008.05.005
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