Amplified Inhibition of Stellate Cell Activation Pathways by PPAR-γ, RAR and RXR Agonists

Peroxisome proliferator activator receptors (PPAR) ligands such as 15-Δ12,13-prostaglandin L(2) [PJ] and all trans retinoic acid (ATRA) have been shown to inhibit the development of liver fibrosis. The role of ligands of retinoic X receptor (RXR) and its ligand, 9-cis, is less clear. The purpose of...

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Bibliographic Details
Main Authors: Sharvit, Efrat, Abramovitch, Shirley, Reif, Shimon, Bruck, Rafael
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3788137/
https://ncbi.nlm.nih.gov/pubmed/24098526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076541
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