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Extracellular Alkaline pH Leads to Increased Metastatic Potential of Estrogen Receptor Silenced Endocrine Resistant Breast Cancer Cells

INTRODUCTION: Endocrine resistance in breast cancer is associated with enhanced metastatic potential and poor clinical outcome, presenting a significant therapeutic challenge. We have established several endocrine insensitive breast cancer lines by shRNA induced depletion of estrogen receptor (ER) b...

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Detalhes bibliográficos
Main Authors: Khajah, Maitham A., Almohri, Iman, Mathew, Princy M., Luqmani, Yunus A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3788134/
https://ncbi.nlm.nih.gov/pubmed/24098477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076327
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