Dual Role of miR-21 in CD4+ T-Cells: Activation-Induced miR-21 Supports Survival of Memory T-Cells and Regulates CCR7 Expression in Naive T-Cells

Immune cell-type specific miRNA expression patterns have been described but the detailed role of single miRNAs in the function of T-cells remains largely unknown. We investigated the role of miR-21 in the function of primary human CD4+ T-cells. MiR-21 is substantially expressed in T-cells with a mem...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Smigielska-Czepiel, Katarzyna, van den Berg, Anke, Jellema, Pytrick, Slezak-Prochazka, Izabella, Maat, Henny, van den Bos, Hilda, van der Lei, Roelof Jan, Kluiver, Joost, Brouwer, Elisabeth, Boots, Anne Mieke H., Kroesen, Bart-Jan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2013
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787993/
https://ncbi.nlm.nih.gov/pubmed/24098447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076217
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg