Evidence for Deep Phylogenetic Conservation of Exonic Splice-Related Constraints: Splice-Related Skews at Exonic Ends in the Brown Alga Ectocarpus Are Common and Resemble Those Seen in Humans

The control of RNA splicing is often modulated by exonic motifs near splice sites. Chief among these are exonic splice enhancers (ESEs). Well-described ESEs in mammals are purine rich and cause predictable skews in codon and amino acid usage toward exonic ends. Looking across species, those with rel...

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Autors principals: Wu, XianMing, Tronholm, Ana, Cáceres, Eva Fernández, Tovar-Corona, Jaime M., Chen, Lu, Urrutia, Araxi O., Hurst, Laurence D.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787667/
https://ncbi.nlm.nih.gov/pubmed/23902749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gbe/evt115
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