Sodium overload due to a persistent current that attenuates the arrhythmogenic potential of a novel LQT3 mutation

Long QT syndrome (LQTS) is a congenital abnormality of cardiac repolarization that manifests as a prolonged QT interval on 12-lead electrocardiograms (ECGs). The syndrome may lead to syncope and sudden death from ventricular tachyarrhythmias known as torsades de pointes. An increased persistent Na(+...

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Hlavní autoři: Moreau, Adrien, Krahn, Andrew D., Gosselin-Badaroudine, Pascal, Klein, George J., Christé, Georges, Vincent, Yohann, Boutjdir, Mohamed, Chahine, Mohamed
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2013
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787509/
https://ncbi.nlm.nih.gov/pubmed/24098284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2013.00126
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