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Heterosynaptic Plasticity Prevents Runaway Synaptic Dynamics

Spike timing-dependent plasticity (STDP) and other conventional Hebbian-type plasticity rules are prone to produce runaway dynamics of synaptic weights. Once potentiated, a synapse would have higher probability to lead to spikes and thus to be further potentiated, but once depressed, a synapse would...

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Main Authors: Chen, Jen-Yung, Lonjers, Peter, Lee, Christopher, Chistiakova, Marina, Volgushev, Maxim, Bazhenov, Maxim
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787503/
https://ncbi.nlm.nih.gov/pubmed/24089497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5088-12.2013
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