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De novo DNA demethylation and noncoding transcription define active intergenic regulatory elements
Deep sequencing of mammalian DNA methylomes has uncovered a previously unpredicted number of discrete hypomethylated regions in intergenic space (iHMRs). Here, we combined whole-genome bisulfite sequencing data with extensive gene expression and chromatin-state data to define functional classes of i...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3787258/ https://ncbi.nlm.nih.gov/pubmed/23811145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.157271.113 |
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