Cognitive-impairing effects of medroxyprogesterone acetate in the rat: independent and interactive effects across time

RATIONALE: The synthetic progestin medroxyprogesterone acetate (MPA), widely used in hormone therapy (HT) and as the contraceptive Depo Provera, is implicated in detrimental cognitive effects in women. Recent evidence in aged ovariectomized (Ovx) rodents shows that short-term MPA treatment impairs c...

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Hauptverfasser: Braden, B. Blair, Garcia, Alexandra N., Mennenga, Sarah E., Prokai, Laszlo, Villa, Stephanie R., Acosta, Jazmin I., Lefort, Natalie, Simard, Alain R., Bimonte-Nelson, Heather A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787203/
https://ncbi.nlm.nih.gov/pubmed/21562760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-011-2322-4
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