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The Krüppel-Like Protein Gli-Similar 3 (Glis3) Functions as a Key Regulator of Insulin Transcription

Transcriptional regulation of insulin in pancreatic β-cells is mediated primarily through enhancer elements located within the 5′ upstream regulatory region of the preproinsulin gene. Recently, the Krüppel-like transcription factor, Gli-similar 3 (Glis3), was shown to bind the insulin (INS) promoter...

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Detalhes bibliográficos
Main Authors: ZeRuth, Gary T., Takeda, Yukimasa, Jetten, Anton M.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787130/
https://ncbi.nlm.nih.gov/pubmed/23927931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1117
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