Impaired Functions of Macrophage from Cystic Fibrosis Patients: CD11b, TLR-5 Decrease and sCD14, Inflammatory Cytokines Increase

BACKGROUND: Early in life, cystic fibrosis (CF) patients are infected with microorganisms. The role of macrophages has largely been underestimated in literature, whereas the focus being mostly on neutrophils and epithelial cells. Macrophages may however play a significant role in the initiating stag...

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Main Authors: Simonin-Le Jeune, Karin, Le Jeune, André, Jouneau, Stéphane, Belleguic, Chantal, Roux, Pierre-François, Jaguin, Marie, Dimanche-Boitre, Marie-Thérèse, Lecureur, Valérie, Leclercq, Caroline, Desrues, Benoît, Brinchault, Graziella, Gangneux, Jean-Pierre, Martin-Chouly, Corinne
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2013
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3787056/
https://ncbi.nlm.nih.gov/pubmed/24098711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075667
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