Mechanisms Involved in the Beneficial Effects of Spironolactone after Myocardial Infarction

INTRODUCTION: Our objective was to analyze the effect of spironolactone on cardiac remodeling after experimental myocardial infarction (MI), assessed by matricellular proteins levels, cardiac collagen amount and distribution, myocardial tissue metalloproteinase inhibitor-1(TIMP-1) concentration, myo...

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Main Authors: Minicucci, Marcos F., dos Santos, Priscila P., Rafacho, Bruna P. M., Gonçalves, Andrea F., Silva, Renata A. C., Chiuso-Minicucci, Fernanda, Azevedo, Paula S., Polegato, Bertha F., Okoshi, Katashi, Pereira, Elenize J., Paiva, Sergio A. R., Zornoff, Leonardo A. M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786966/
https://ncbi.nlm.nih.gov/pubmed/24098808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076866
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