The Distribution and ‘In Vivo’ Phase Variation Status of Haemoglobin Receptors in Invasive Meningococcal Serogroup B Disease: Genotypic and Phenotypic Analysis

Two haemoglobin-binding proteins, HmbR and HpuAB, contribute to iron acquisition by Neisseria meningitidis. These receptors are subject to high frequency, reversible switches in gene expression - phase variation (PV) - due to mutations in homopolymeric (poly-G) repeats present in the open reading fr...

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Main Authors: Lucidarme, Jay, Findlow, Jamie, Chan, Hannah, Feavers, Ian M., Gray, Stephen J., Kaczmarski, Edward B., Parkhill, Julian, Bai, Xilian, Borrow, Ray, Bayliss, Christopher D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786947/
https://ncbi.nlm.nih.gov/pubmed/24098814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076932
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