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The Uremic Toxin Indoxyl Sulphate Enhances Macrophage Response to LPS

Indoxyl sulphate (IS) is a protein-bound uremic toxin that results from the metabolism of dietary tryptophan normally excreted by kidney through the proximal tubules. Thus the toxin accumulates in the blood of patients with impaired renal function such as in chronic kidney disease (CKD). High IS ser...

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Hlavní autoři: Adesso, Simona, Popolo, Ada, Bianco, Giuseppe, Sorrentino, Rosalinda, Pinto, Aldo, Autore, Giuseppina, Marzocco, Stefania
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786936/
https://ncbi.nlm.nih.gov/pubmed/24098806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076778
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