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Combined Inhibition of Autophagy and Caspases Fails to Prevent Developmental Nurse Cell Death in the Drosophila melanogaster Ovary

During the final stages of Drosophila melanogaster oogenesis fifteen nurse cells, sister cells to the oocyte, degenerate as part of normal development. This process involves at least two cell death mechanisms, caspase-dependent cell death and autophagy, as indicated by apoptosis and autophagy marker...

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Bibliographic Details
Main Authors: Peterson, Jeanne S., McCall, Kimberly
Format: Artigo
Language:Inglês
Published: Public Library of Science 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786910/
https://ncbi.nlm.nih.gov/pubmed/24098761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076046
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