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Intrinsic Bio-Signature of Gene Delivery Nanocarriers May Impair Gene Therapy Goals

Non-viral lipid/polymeric vectors have widely been used as nanocarriers (NCs) for gene delivery. They possess large surface area to volume ratio and are able to interact with biomolecules through functional moieties, resulting in inadvertent biological impacts, in particular at genomic level. Thus,...

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Bibliographische Detailangaben
Hauptverfasser: Barar, Jaleh, Omidi, Yadollah
Format: Artigo
Sprache:Inglês
Veröffentlicht: Tabriz University of Medical Sciences 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786791/
https://ncbi.nlm.nih.gov/pubmed/24163801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5681/bi.2013.028
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