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A Novel Model of T(H)2-polarized Chronic Ileitis: The SAMP1 Mouse

BACKGROUND & AIMS: SAMP1/Yit mice develop spontaneous, segmental, transmural ileitis recapitulating many features of Crohn’s disease (CD). The ileitic phenotype may have arisen during crosses of SAMP1 mice selected for the presence of skin lesions. We hereby describe that the original SAMP1 stra...

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Huvudupphovsmän: McNamee, Eoin N., Wermers, Joshua D., Masterson, Joanne C., Collins, Colm B., Lebsack, Matthew D.P., Fillon, Sophie, Robinson, Zachary D., Grenawalt, Joanna, Lee, James J., Jedlicka, Paul, Furuta, Glenn T., Rivera-Nieves, Jesús
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2010
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786705/
https://ncbi.nlm.nih.gov/pubmed/19856411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21148
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