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Bicuspid aortic valve and aortic coarctation are linked to deletion of the X chromosome short arm in Turner syndrome

BACKGROUND: Congenital heart disease (CHD) is a cardinal feature of X chromosome monosomy, or Turner syndrome (TS). Haploinsufficiency for gene(s) located on Xp have been implicated in the short stature characteristic of the syndrome, but the chromosomal region related to the CHD phenotype has not b...

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Главные авторы: Bondy, Carolyn, Bakalov, Vladimir K, Cheng, Clara, Olivieri, Laura, Rosing, Douglas R, Arai, Andrew E
Формат: Artigo
Язык:Inglês
Опубликовано: BMJ Publishing Group 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786649/
https://ncbi.nlm.nih.gov/pubmed/23825392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2013-101720
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