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X-chromosome linked inhibitor of apoptosis protein inhibits muscle proteolysis in insulin-deficient mice

Loss of muscle protein is a serious complication of catabolic diseases and contributes substantially to patients' morbidity and mortality. This muscle loss is mediated largely by the activation of the ubiquitin–proteasome system; however, caspase-3 catalyzes an initial step in this process by c...

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Detalhes bibliográficos
Main Authors: Wang, XH, Hu, J, Du, J, Klein, JD
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786557/
https://ncbi.nlm.nih.gov/pubmed/17315041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.gt.3302927
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