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Nitrososynthase triggered oxidative carbon-carbon bond cleavage in baumycin biosynthesis

Baumycins are coproduced with clinically important anticancer secondary metabolites daunorubicin and doxorubicin, which are glycosylated anthracyclines isolated from Streptomyces peucetius. The distinguishing feature of baumycins is the presence of an unusual acetal moiety appended to daunosamine, w...

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Detalhes bibliográficos
Main Authors: Al-Mestarihi, Ahmad, Romo, Anthony, Liu, Hung-wen, Bachmann, Brian O.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786440/
https://ncbi.nlm.nih.gov/pubmed/23885759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja404987r
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