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Induction of tumor cell apoptosis by a novel class of N-thiolated β-lactam antibiotics with structural modifications at N(1) and C(3) of the lactam ring
The investigation of novel anti-tumor agents that preferentially select for malignant cells with a tolerable toxicity level has been the focus of anti-cancer drug discovery. Our laboratories have previously reported that certain N-alkylthiolated β-lactams had DNA-damaging and apoptosis-inducing acti...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3786433/ https://ncbi.nlm.nih.gov/pubmed/18506361 |
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