Variants within the immunoregulatory CBLB gene are associated with Multiple Sclerosis

A genome wide association scan of ~6.6 million genotyped or imputed variants in 882 Sardinian Multiple Sclerosis (MS) cases and 872 controls suggested association of CBLB gene variants with disease, which was confirmed in 1,775 cases and 2,005 controls (overall P =1.60 × 10(-10)). CBLB encodes a neg...

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Main Authors: Sanna, Serena, Pitzalis, Maristella, Zoledziewska, Magdalena, Zara, Ilenia, Sidore, Carlo, Murru, Raffaele, Whalen, Michael B., Busonero, Fabio, Maschio, Andrea, Costa, Gianna, Melis, Maria Cristina, Deidda, Francesca, Poddie, Fausto, Morelli, Laura, Farina, Gabriele, Li, Yun, Dei, Mariano, Lai, Sandra, Mulas, Antonella, Cuccuru, Gianmauro, Porcu, Eleonora, Liang, Liming, Zavattari, Patrizia, Moi, Loredana, Deriu, Elisa, Urru, M. Francesca, Bajorek, Michele, Satta, Maria Anna, Cocco, Eleonora, Ferrigno, Paola, Sotgiu, Stefano, Pugliatti, Maura, Traccis, Sebastiano, Angius, Andrea, Melis, Maurizio, Rosati, Giulio, Abecasis, Gonçalo R., Uda, Manuela, Marrosu, Maria Giovanna, Schlessinger, David, Cucca., Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786343/
https://ncbi.nlm.nih.gov/pubmed/20453840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.584
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