Convection-enhanced delivery of M13 bacteriophage to the brain

OBJECT: Recent studies indicate that M13 bacteriophage, a very large nanoparticle, binds to β-amyloid and α-synuclein proteins, leading to plaque disaggregation in models of Alzheimer and Parkinson disease. To determine the feasibility, safety, and characteristics of convection-enhanced delivery (CE...

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Detaylı Bibliyografya
Asıl Yazarlar: Ksendzovsky, Alexander, Walbridge, Stuart, Saunders, Richard C., Asthagiri, Ashok R., Heiss, John D., Lonser, Russell R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786326/
https://ncbi.nlm.nih.gov/pubmed/22606981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2012.4.JNS111528
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