A serotonin-induced N-glycan switch regulates platelet aggregation

Serotonin (5-HT) is a multifunctional signaling molecule that plays different roles in a concentration-dependent manner. We demonstrated that elevated levels of plasma 5-HT accelerate platelet aggregation resulting in a hypercoagulable state in which the platelet surface becomes occupied by several...

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Main Authors: Mercado, Charles P., Quintero, Maritza V., Li, Yicong, Singh, Preeti, Byrd, Alicia K., Talabnin, Krajang, Ishihara, Mayumi, Azadi, Parastoo, Rusch, Nancy J., Kuberan, Balagurunathan, Maroteaux, Luc, Kilic, Fusun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786303/
https://ncbi.nlm.nih.gov/pubmed/24077408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02795
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