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Elevated Glucocorticoids during Ovine Pregnancy increase Appetite and produce Glucose Dysregulation and Adiposity in Their Granddaughters in response to ad libitum feeding at one year of age

OBJECTIVE: Synthetic glucocorticoids (sGC) are administered to women threatening preterm labor. We have shown multi-generational endocrine and metabolic effects of fetal sGC exposure. We hypothesized that sGC exposure would alter the second filial generation (F2) offspring neonatal leptin peak that...

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Detalhes bibliográficos
Main Authors: Long, Nathan M., Smith, Derek. T., Ford, Stephen P., Nathanielsz, Peter W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3786012/
https://ncbi.nlm.nih.gov/pubmed/23727517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2013.05.051
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