Real-Time Visualization of Assembling of a Sphingomyelin-Specific Toxin on Planar Lipid Membranes

Pore-forming toxins (PFTs) are soluble proteins that can oligomerize on the cell membrane and induce cell death by membrane insertion. PFT oligomers sometimes form hexagonal close-packed (hcp) structures on the membrane. Here, we show the assembling of the sphingomyelin (SM)-binding PFT, lysenin, in...

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Bibliografske podrobnosti
Main Authors: Yilmaz, Neval, Yamada, Taro, Greimel, Peter, Uchihashi, Takayuki, Ando, Toshio, Kobayashi, Toshihide
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2013
Teme:
Membrane
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785888/
https://ncbi.nlm.nih.gov/pubmed/24047991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.07.052
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