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Molecular Recognition of CXCR4 by a Dual Tropic HIV-1 gp120 V3 Loop

HIV-1 cell entry is initiated by the interaction of the viral envelope glycoprotein gp120 with CD4, and chemokine coreceptors CXCR4 and CCR5. The molecular recognition of CXCR4 or CCR5 by the HIV-1 gp120 is mediated through the V3 loop, a fragment of gp120. The binding of the V3 loop to CXCR4 or CCR...

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Bibliografski detalji
Glavni autori: Tamamis, Phanourios, Floudas, Christodoulos A.
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785887/
https://ncbi.nlm.nih.gov/pubmed/24048002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.07.049
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