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A chemostat array enables the spatio-temporal analysis of the yeast proteome

Observing cellular responses to perturbations is central to generating and testing hypotheses in biology. We developed a massively parallel microchemostat array capable of growing and observing 1,152 yeast-GFP strains on the single-cell level with 20 min time resolution. We measured protein abundanc...

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Detalhes bibliográficos
Main Authors: Dénervaud, Nicolas, Becker, Johannes, Delgado-Gonzalo, Ricard, Damay, Pascal, Rajkumar, Arun S., Unser, Michael, Shore, David, Naef, Felix, Maerkl, Sebastian J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785771/
https://ncbi.nlm.nih.gov/pubmed/24019481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1308265110
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