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Oligomerization of DDR1 ECD affects receptor-ligand binding

Discoidin Domain Receptor 1 (DDR1) is a widely expressed receptor tyrosine kinase (RTK) which regulates cell differentiation, proliferation and migration and remodeling of the extracellular matrix. Collagen(s) are the only known ligand for DDR1. We have previously reported that collagen stimulation...

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Detalles Bibliográficos
Main Authors: Yeung, David, Chmielewski, David, Mihai, Cosmin, Agarwal, Gunjan
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785576/
https://ncbi.nlm.nih.gov/pubmed/23810922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2013.06.010
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