Upregulation of Tissue Factor by Activated Stat3 Contributes to Malignant Pleural Effusion Generation via Enhancing Tumor Metastasis and Vascular Permeability in Lung Adenocarcinoma

Malignant pleural effusion (MPE) is a poor prognostic sign for patients with lung cancer. Tissue factor (TF) is a coagulation factor that participates in angiogenesis and vascular permeability and is abundant in MPE. We previously demonstrated that autocrine IL-6-activated Stat3 contributes to tumor...

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Detalhes bibliográficos
Main Authors: Yeh, Hsuan-Heng, Chang, Wen-Tsan, Lu, Kuang-Chu, Lai, Wu-Wei, Liu, Hsiao-Sheng, Su, Wu-Chou
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785526/
https://ncbi.nlm.nih.gov/pubmed/24086497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075287
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