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The Influence of Transcription Factor Competition on the Relationship between Occupancy and Affinity

Transcription factors (TFs) are proteins that bind to specific sites on the DNA and regulate gene activity. Identifying where TF molecules bind and how much time they spend on their target sites is key to understanding transcriptional regulation. It is usually assumed that the free energy of binding...

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Detalhes bibliográficos
Main Authors: Zabet, Nicolae Radu, Foy, Robert, Adryan, Boris
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785477/
https://ncbi.nlm.nih.gov/pubmed/24086290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073714
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