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The Influence of Transcription Factor Competition on the Relationship between Occupancy and Affinity
Transcription factors (TFs) are proteins that bind to specific sites on the DNA and regulate gene activity. Identifying where TF molecules bind and how much time they spend on their target sites is key to understanding transcriptional regulation. It is usually assumed that the free energy of binding...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3785477/ https://ncbi.nlm.nih.gov/pubmed/24086290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073714 |
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