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Estrogen Receptor Alpha and Nuclear Factor Y Coordinately Regulate the Transcription of the SUMO-Conjugating UBC9 Gene in MCF-7 Breast Cancer Cells

UBC9 encodes a protein that conjugates small ubiquitin-related modifier (SUMO) to target proteins thereby changing their functions. Recently, it was noted that UBC9 expression and activity play a role in breast tumorigenesis and response to anticancer drugs. However, the underlying mechanism is poor...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ying, Shibo, Dünnebier, Thomas, Si, Jing, Hamann, Ute
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785449/
https://ncbi.nlm.nih.gov/pubmed/24086615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075695
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