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SQSTM1/p62 Interacts with HDAC6 and Regulates Deacetylase Activity

Protein aggregates can form in the cytoplasm of the cell and are accumulated at aggresomes localized to the microtubule organizing center (MTOC) where they are subsequently degraded by autophagy. In this process, aggregates are engulfed into autophagosomes which subsequently fuse with lysosomes for...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yan, Jin, Seibenhener, Michael Lamar, Calderilla-Barbosa, Luis, Diaz-Meco, Maria-Theresa, Moscat, Jorge, Jiang, Jianxiong, Wooten, Marie W., Wooten, Michael C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785417/
https://ncbi.nlm.nih.gov/pubmed/24086678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076016
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