Salmonella require the fatty acid regulator PPARδ for the establishment of a metabolic environment essential for long term persistence

Host adapted Salmonella strains are responsible for a number of disease manifestations in mammals, including an asymptomatic chronic infection where bacteria survive within macrophages located in systemic sites. However, the host cell physiology and metabolic requirements supporting bacterial persis...

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Main Authors: Eisele, Nicholas A., Ruby, Thomas, Jacobson, Amanda, Manzanillo, Paolo S., Cox, Jeffery S., Lam, Lilian, Mukundan, Lata, Chawla, Ajay, Monack, Denise M.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785333/
https://ncbi.nlm.nih.gov/pubmed/23954156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2013.07.010
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