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Does Study Design Influence Outcome? The Effects of Placebo Control and Treatment Duration in Antidepressant Trials

BACKGROUND: Clinicians and researchers synthesize data from randomized controlled trials (RCTs) of antidepressants to make conclusions about the efficacy of medications for depression. All treatments include nonspecific factors in addition to the specific effects of drugs, and study design may influ...

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Detalhes bibliográficos
Main Authors: Rutherford, Bret R, Sneed, Joel R., Roose, Steven P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785090/
https://ncbi.nlm.nih.gov/pubmed/19321970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000209348
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