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In Vivo Analysis of Lrig Genes Reveals Redundant and Independent Functions in the Inner Ear

Lrig proteins are conserved transmembrane proteins that modulate a variety of signaling pathways from worm to humans. In mammals, there are three family members – Lrig1, Lrig2, and Lrig3 – that are defined by closely related extracellular domains with a similar arrangement of leucine rich repeats an...

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Detalhes bibliográficos
Main Authors: del Rio, Tony, Nishitani, Allison M., Yu, Wei-Ming, Goodrich, Lisa V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784559/
https://ncbi.nlm.nih.gov/pubmed/24086156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003824
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