Rapid Intrahost Evolution of Human Cytomegalovirus Is Shaped by Demography and Positive Selection

Populations of human cytomegalovirus (HCMV), a large DNA virus, are highly polymorphic in patient samples, which may allow for rapid evolution within human hosts. To understand HCMV evolution, longitudinally sampled genomic populations from the urine and plasma of 5 infants with symptomatic congenit...

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Main Authors: Renzette, Nicholas, Gibson, Laura, Bhattacharjee, Bornali, Fisher, Donna, Schleiss, Mark R., Jensen, Jeffrey D., Kowalik, Timothy F.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784496/
https://ncbi.nlm.nih.gov/pubmed/24086142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003735
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