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The Suf Iron-Sulfur Cluster Synthesis Pathway Is Required for Apicoplast Maintenance in Malaria Parasites

The apicoplast organelle of the malaria parasite Plasmodium falciparum contains metabolic pathways critical for liver-stage and blood-stage development. During the blood stages, parasites lacking an apicoplast can grow in the presence of isopentenyl pyrophosphate (IPP), demonstrating that isoprenoid...

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Autors principals: Gisselberg, Jolyn E., Dellibovi-Ragheb, Teegan A., Matthews, Krista A., Bosch, Gundula, Prigge, Sean T.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784473/
https://ncbi.nlm.nih.gov/pubmed/24086138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003655
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