Next-Generation Sequence Analysis of Cancer Xenograft Models

Next-generation sequencing (NGS) studies in cancer are limited by the amount, quality and purity of tissue samples. In this situation, primary xenografts have proven useful preclinical models. However, the presence of mouse-derived stromal cells represents a technical challenge to their use in NGS s...

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Detalhes bibliográficos
Main Authors: Rossello, Fernando J., Tothill, Richard W., Britt, Kara, Marini, Kieren D., Falzon, Jeanette, Thomas, David M., Peacock, Craig D., Marchionni, Luigi, Li, Jason, Bennett, Samara, Tantoso, Erwin, Brown, Tracey, Chan, Philip, Martelotto, Luciano G., Watkins, D. Neil
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784448/
https://ncbi.nlm.nih.gov/pubmed/24086345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074432
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