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Rapamycin unbalances the polarization of human macrophages to M1
Plasticity is a hallmark of macrophages, and in response to environmental signals these cells undergo different forms of polarized activation, the extremes of which are called classic (M1) and alternative (M2). Rapamycin (RAPA) is crucial for survival and functions of myeloid phagocytes, but its eff...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3784164/ https://ncbi.nlm.nih.gov/pubmed/23710834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12126 |
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