Role of the Promoter Polymorphism IL-6 −174G/C in Dermatomyositis and Systemic Lupus Erythematosus

The promoter polymorphism −174G/C within the interleukin-6 gene (IL-6) has been reported to have a functional importance through the modulation of IL-6 gene expression in vitro and in vivo. IL-6 is thought to play an important role in autoimmune diseases and the effect of its receptor inhibitor—toci...

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Detalhes bibliográficos
Main Authors: Hristova, Maria, Dourmishev, Lyubomir, Kamenarska, Zornitsa, Nikolova, Svetla, Kaneva, Radka, Vinkov, Anton, Baleva, Marta, Monova, Daniela, Mitev, Vanio
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784074/
https://ncbi.nlm.nih.gov/pubmed/24106699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/315365
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